Dr. Sultani Hadley Matendechero is a prominent figure in Kenya's healthcare leadership, currently serving as the Deputy Director General for Health. With nearly two decades of experience as a consultant Clinical Pharmacist, Dr. Matendechero has made significant contributions to public health management and clinical practice. His pivotal role in establishing the Kenya National Public Health Institute underscores his commitment to advancing healthcare infrastructure and policy in Kenya. Dr. Sultani's impact extends beyond national borders, highlighted by his influential positions in global health initiatives. Notably, he is currently serving as Vice Chair of the World Health Organization’s Working Group on amendments to the International Health Regulations (WGIHR), showcasing his leadership in shaping international health governance. Dr. Matendechero's dedication to combating neglected tropical diseases (NTDs) is evident through his leadership as the first Chair of the African NTD Program Managers’ Community of Practice and current Chair of the Leishmaniasis East Africa Platform. He brings a wealth of expertise to numerous strategic advisory groups at global, regional, and domestic levels. A passionate advocate for evidence-based public health strategies, Dr. Sultani has authored and co-authored over 50 operational research publications in esteemed peer-reviewed journals. His commitment to equity, increased domestic financing for health, and robust health promotion and disease prevention initiatives underscores his vision for successful global health programs. Dr. Sultani Hadley Matendechero's leadership and expertise make him a valuable asset to the international community, particularly in empowering African women in health leadership to drive impactful change within the global health landscape.